Rhizarthrosis is a degenerative joint disease that affects the saddle joint of the thumb. This joint is located at the base of the thumb and plays an important role in the mobility and functionality of the hand. Rhizarthrosis involves a breakdown of the articular cartilage and inflammation in the area of the thumb saddle joint, which can lead to pain, stiffness, limited mobility and possibly even impairment of everyday activities. The disease often affects middle-aged to older people and can be triggered by factors such as overuse, injuries or genetics. Treatment options for rhizarthrosis range from conservative approaches such as pain management, physical therapy, and hand orthoses to more advanced treatments such as injections and, in some cases, surgery. Early diagnosis and individually tailored therapy are crucial to improving the quality of life of those affected and maintaining the functionality of their hands.